Risk factors associated with mortality in severely ill COVID-19 patients: cohort study

Authors

  • Ricardo Alfonso Merchán-Chaverra Clínica Colsanitas https://orcid.org/0000-0002-7962-403X
  • Jhoana Patricia Ruiz-Jiménez Clínica Colsanitas
  • Diana Marcela Sotelo-Vergara 1Unidad de Cuidado Intensivo, Clínica Infantil Santa María del Lago, Clínica Colsanitas, Grupo Keralty, Bogotá, Colombia 2Grupo de Investigación en Nutrición Clínica y Rehabilitación, Fundación Universitaria Sanitas, Clínica Colsanitas, Grupo Keralty, Bogotá, Colombia
  • Mónica Vanessa Carrillo-Ramirez Clínica Colsanitas
  • Jennyfer Carolina Jacome-Suarez Clínica Colsanitas
  • Jorge Medina-Parra Fundación Universitaria Sanitas image/svg+xml
  • Jorge Iván Alvarado-Sanchez Fundación Santa Fe de Bogotá image/svg+xml
  • Iván Camilo Alarcón-Amaya Clínica Colsanitas

DOI:

https://doi.org/10.35454/rncm.v6n4.527

Keywords:

COVID-19, Mortality, Comorbidity, Nutrition, Obesity

Abstract

Background: Patients diagnosed with COVID-19 who require intensive care unit (ICU) demand multidisciplinary care, which is decisive for their intervention and prognosis. The objective of this study was to identify the risk factors for mortality in critically ill COVID-19 patients in Bogota, Colombia. 

Methods: This was a retrospective descriptive study (from March 2020 to February 2021) which included critically ill COVID-19 patients admitted to the ICU. Electronic medical records were reviewed, and demographic and clinical data were collected. A logistic regression model was performed. Mortality was considered as the dependent variable, and the clinical and demographic variables as explanatory factors. 

Results: We included 562 patients with an overall mortality of 42%, associated comorbidities such as diabetes mellitus (51%), grade 2 obesity (75%), and age over 65 years (51%). The logistic regression model showed that patients over 65 years of age [odds ratio (OR): 3.23 (2.28 - 4.59)]; diabetes mellitus [OR: 1.68 (1.16 - 2.44)], and grade 2 obesity [OR: 3.5 (1.31 - 9.77)] were risk factors for mortality in COVID-19 patients at the ICU. 

Conclusion: This study reported that age over 65 years, diabetes mellitus, and grade 2 obesity were risk factors for death in critically ill COVID-19 patients. 

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Author Biography

Ricardo Alfonso Merchán-Chaverra, Clínica Colsanitas

Clinica Universitaria Colombia

Bogotá, Colombia

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Published

2023-11-09

How to Cite

Merchán-Chaverra, R. A., Ruiz-Jiménez, J. P. ., Sotelo-Vergara, D. M. ., Carrillo-Ramirez, M. V. ., Jacome-Suarez, J. C., Medina-Parra, J., Alvarado-Sanchez, J. I. ., & Alarcón-Amaya, I. C. . (2023). Risk factors associated with mortality in severely ill COVID-19 patients: cohort study. Journal Clinical Nutrition and Metabolism, 6(4), 5–13. https://doi.org/10.35454/rncm.v6n4.527