Implicaciones clínicas e inmunológicas de los micronutrientes durante la infección por VIH

Iván A. Osuna- Padilla; Nadia Carolina Rodríguez Moguel; Adriana Aguilar Vargas; Olivia Briceño

doi:10.35454/rncm.v3n2.166

Autores/as

Iván A. Osuna- Padilla https://orcid.org/0000-0002-3490-3414
Nadia Carolina Rodríguez Moguel Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias
Adriana Aguilar Vargas Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias
Olivia Briceño Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias

DOI:

https://doi.org/10.35454/rncm.v3n2.166

Palabras clave:

VIH, Terapia nutricional, Inflamación, Micronutrientes

Resumen

Durante la infección por VIH existe una alteración en las funciones del sistema inmunológico e inflamación crónica que no logra resolverse con el tratamiento antirretroviral (TAR). Aunado a lo anterior, se ha reportado una alta prevalencia de deficiencia de micronutrientes en la población VIH+ debido a un aumento en la demanda y en la excreción de los mismos.

Dicha inflamación crónica y deficiencia de micronutrientes está asociada a la aparición de comorbilidades no asociadas al síndrome de inmunodeficiencia adquirida (SIDA) como hipertensión arterial, enfermedades cardiovasculares, síndrome metabólico, cáncer y osteoporosis. Es necesario desarrollar estrategias dirigidas a regular la inflamación y activación crónica presente en los individuos VIH+ bajo TAR para mejorar su calidad de vida y disminuir la prevalencia de comorbilidades. Una opción prometedora es la intervención nutricional a través de la suplementación de micronutrientes que han demostrado tener un efecto regulador de la inflamación y de la respuesta inmunológica y que podrían representar una opción segura y costo eficiente.

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Biografía del autor/a

Iván A. Osuna- Padilla

Licenciado en Nutrición, Universidad Autónoma de Durango. Maestro en Nutrición Clínica, Instituto Nacional de Salud Pública. Doctor en Investigación en Medicina, Instituto Politécnico Nacional. Nutriólogo Certificado, Colegio Mexicano de Nutriólogos. Nutriólogo clínico. Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias, Ciudad de México.

Nadia Carolina Rodríguez Moguel, Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias

Licenciada en Nutrición, Maestra en Ciencias.

Diplomado en Soporte nutricional

Diplomado en Nutrición Clínica Perinatal

Adriana Aguilar Vargas, Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias

Licenciada en Nutrición y Ciencias de los Alimentos

Maestra en Ciencias de la Nutrición

Olivia Briceño, Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias

Licenciada Químico Farmaceutico Biólogo, UNAM

Maestra en Ciencias Biológicas, UNAM

Doctora en Inmunología, Pasteur Institute

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