Vitamin B12 Pharmaconutrition for COVID-19

William Manzanares; Gil Hardy

doi:10.35454/rncm.v4n1.187

Autores

William Manzanares Facultad de Medicina, Universidad de la República http://orcid.org/0000-0002-6060-0329
Gil Hardy

DOI:

https://doi.org/10.35454/rncm.v4n1.187

Palavras-chave:

Farmaconutrição, COVID-19, Vitamina B12, SDRA, Terapia intensiva

Resumo

A mortalidade pela doença de Covid-19 é muito maior em idosos, muitos dos quais sucumbem à síndrome de dificuldade respiratória aguda (SDRA) desencadeada pela infecção viral. A vitamina B12 parenteral em altas doses oferece uma nova terapia promissora para pacientes com Covid-19 com SDRA decorrente de sepse / choque séptico. As propriedades antiinflamatórias e antioxidantes da vitamina B12 e das transcobalaminas podem modular a inflamação sistêmica que contribui para a cascata de citocinas que leva à SDRA. Estudos clínicos são necessários para estabelecer um regime apropriado para administrar vitamina B12 como um farmaconutriente para pacientes criticamente doentes com Covid-19.

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Biografia do Autor

Gil Hardy

Auckland, Nueva Zelanda

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