Risk factors of nutritional origin associated with the development of Intensive Care Unit-acquired weakness: Narrative review
DOI:
https://doi.org/10.35454/rncm.v6n2.503Keywords:
Acquired polyneuropathy, Critical illness, Body composition, Hyperglycemia, Autophagy, Caloric restrictionAbstract
Intensive Care Unit-Acquired Weakness (ICU-AW) is defined as the decrease in muscle strength and functionality in critically ill patients with no other possible cause than their critical condition. Different risk factors associated with the development of ICU-AW have been reported, which have a partial or total effect on the deterioration of muscle fibers; however, some of the risk factors associated with nutritional status continue to be given a low priority, given the lack of awareness regarding the clinical benefits of addressing them. The aim of this narrative review is to collect information on modifiable risk factors of nutritional origin related to the development of ICU-AW and provide recommendations for its prevention. A search was conducted of scientific literature in English and Spanish in databases and search engines (PubMed, Springer Link and Medline) using the MeSH terms: “acquired polyneuropathy”, “critical illness”, “body composition”, “hyperglycemia”, “autophagy”, “caloric restriction”. Although different risk factors of nutritional origin have been proposed, however, there is no conclusive evidence regarding their relationship with the prevention of ICU-AW. The identification of risk factors for the development of weakness, mainly those that are potentially modifiable, is the main strategy for the prevention of this clinical entity. Additional information is required on the relationship between these risk factors, especially those of nutritional origin, and the development of ICU-AW, especially those of nutritional origin.
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