Relationship between bile acids and intestinal microbiota, can it be considered an etiological factor in various cholangiopathies? A narrative review
DOI:
https://doi.org/10.35454/rncm.v4n4.287Keywords:
Microbiota, Bile Acid, CholangiopathyAbstract
Bile acids, whose precursor is dietary cholesterol, are essential for the metabolism of ingested lipids. This is perhaps the role they are best known for. However, they are also involved in a reciprocal interaction with intestinal bacterial metabolism through molecular signals that allow a change in both the abundance and diversity of the gut microbiota. In recent years, the latter has been considered as the “new organ” and earned an in-depth study facilitated by advances and optimization in diagnostic methods, allowing to determine its role in diseases, not only of the gastrointestinal tract, but also at the systemic level.
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