Éxito de la cirugía bariátrica: perspectiva biológica

Edna J Nava-González; Brenda K. Delgadillo Arteaga

doi:10.35454/rncm.v4n4.286

Autores/as

Edna J Nava-González Universidad Autónoma de Nuevo León https://orcid.org/0000-0001-8818-2600
Brenda K. Delgadillo Arteaga Universidad Autónoma del Estado de México https://orcid.org/0000-0003-2048-0614

DOI:

https://doi.org/10.35454/rncm.v4n4.286

Palabras clave:

Cirugía bariátrica, Metabolismo, Balance energético

Resumen

La obesidad se define como una acumulación anormal o excesiva de grasa corporal, que puede alcanzar grados capaces de afectar la salud. Se sabe que existe una correlación directa con el aumento del índice de masa corporal (IMC) y la prevalencia de comorbilidades, lo que genera un impacto negativo en la esperanza de vida y el gasto en salud pública. Entre todos los tratamientos para la obesidad disponibles, la cirugía bariátrica es la que presenta mejores resultados en la pérdida de exceso de peso y remisión de comorbilidades, y produce efectos positivos en la función del tejido adiposo, la sensibilidad a la insulina, el contenido y función de la grasa hepática, así como la mejoría en general del metabolismo y, en consecuencia, aumenta la calidad de vida a largo plazo. Las mejorías biológicas y metabólicas son posibles en pacientes con obesidad grave después de la cirugía bariátrica.

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Citas

Badman MK, Flier JS. The gut and energy balance: visceral allies in the obesity wars. Science. 2005;307(5717):1909-14. doi: 10.1126/science.1109951

Cavin JB, Couvelard A, Lebtahi R, Ducroc R, Arapis K, Voitellier E, et al. Differences in Alimentary Glucose Absorption and Intestinal Disposal of Blood Glucose After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy. Gastroenterology. 2016;150(2):454-64.e9. doi: 10.1053/j.gastro.2015.10.009

Ziogas IA, Zapsalis K, Giannis D, Tsoulfas G. Metabolic syndrome and liver disease in the era of bariatric surgery: What you need to know! World J Hepatol. 2020;12(10):709-721. doi: 10.4254/wjh.v12.i10.709

Angrisani L, Santonicola A, Iovino P, Formisano G, Buchwald H, Scopinaro N. Bariatric Surgery Worldwide 2013. Obes Surg. 2015;25(10):1822-32. doi: 10.1007/s11695-015-1657-z

Molin Netto BD, Earthman CP, Farias G, Landi Masquio DC, Grotti Clemente AP, Peixoto P, et al. Eating patterns and food choice as determinant of weight loss and improvement of metabolic profile after RYGB. Nutrition. 2017;33:125-131. doi: 10.1016/j.nut.2016.05.007

Holst JJ, Madsbad S, Bojsen-Møller KN, Svane MS, Jørgensen NB, Dirksen C, et al. Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss. Surg Obes Relat Dis. 2018;14(5):708-714. doi: 10.1016/j.soard.2018.03.003

Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219-34. doi: 10.1111/joim.12012

Zhang C, Zhang J, Liu Z, Zhou Z. More than an Anti-diabetic Bariatric Surgery, Metabolic Surgery Alleviates Systemic and Local Inflammation in Obesity. Obes Surg. 2018;28(11):3658-3668. doi: 10.1007/s11695-018-3400-z

Kaska L, Sledzinski T, Chomiczewska A, Dettlaff-Pokora A, Swierczynski J. Improved glucose metabolism following bariatric surgery is associated with increased circulating bile acid concentrations and remodeling of the gut microbiome. World J Gastroenterol. 2016;22(39):8698-8719. doi: 10.3748/wjg.v22.i39.8698

Laferrère B, Heshka S, Wang K, Khan Y, McGinty J, Teixeira J, et al. Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes. Diabetes Care. 2007;30(7):1709-16. doi: 10.2337/dc06-1549

Price PH, Kaizer AM, Inge TH, Eckel RH. Physical activity impacts insulin sensitivity post metabolic bariatric surgery in adolescents with severe obesity. Int J Obes (Lond). 2020;44(7):1479-1486. doi: 10.1038/s41366-020-0585-8

Berthoud HR, Morrison CD, Münzberg H. The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed? Physiol Behav. 2020;222:112959. doi: 10.1016/j.physbeh.2020.112959

Leibel RL, Seeley RJ, Darsow T, Berg EG, Smith SR, Ratner R. Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium. Diabetes. 2015;64(7):2299-309. doi: 10.2337/db15-0004

Berthoud HR, Shin AC, Zheng H. Obesity surgery and gut-brain communication. Physiol Behav. 2011;105(1):106-19. doi: 10.1016/j.physbeh.2011.01.023

Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 2002;346(21):1623-30. doi: 10.1056/NEJMoa012908

Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Aminian A, Brethauer SA, et al. Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes. N Engl J Med. 2017;376(7):641-651. doi: 10.1056/NEJMoa1600869

Melby CL, Paris HL, Foright RM, Peth J. Attenuating the Biologic Drive for Weight Regain Following Weight Loss: Must What Goes Down Always Go Back Up? Nutrients. 2017;9(5):468. doi: 10.3390/nu9050468

Foright RM, Presby DM, Sherk VD, Kahn D, Checkley LA, Giles ED, et al. Is regular exercise an effective strategy for weight loss maintenance? Physiol Behav. 2018;188:86-93. doi: 10.1016/j.physbeh.2018.01.025

Andrew CA, Umashanker D, Aronne LJ, Shukla AP. Intestinal and Gastric Origins for Diabetes Resolution After Bariatric Surgery. Curr Obes Rep. 2018;7(2):139-146. doi: 10.1007/s13679-018-0302-2

Stylopoulos N, Davis P, Pettit JD, Rattner DW, Kaplan LM. Changes in serum ghrelin predict weight loss after Roux-en-Y gastric bypass in rats. Surg Endosc. 2005;19(7):942-6. doi: 10.1007/s00464-004-8825-x

Jakobsen GS, Småstuen MC, Sandbu R, Nordstrand N, Hofsø D, Lindberg M, et al. Association of Bariatric Surgery vs Medical Obesity Treatment With Long-term Medical Complications and Obesity-Related Comorbidities. JAMA. 2018;319(3):291-301. doi: 10.1001/jama.2017.21055

Mackenzie H, Markar SR, Askari A, Faiz O, Hull M, Purkayastha S, et al. Obesity surgery and risk of cancer. Br J Surg. 2018;105(12):1650-1657. doi: 10.1002/bjs.10914

Sjöström L, Narbro K, Sjöström CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741-52. doi: 10.1056/NEJMoa066254

Sjöström L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683-93. doi: 10.1056/NEJMoa035622

Karason K, Lindroos AK, Stenlöf K, Sjöström L. Relief of cardiorespiratory symptoms and increased physical activity after surgically induced weight loss: results from the Swedish Obese Subjects study. Arch Intern Med. 2000;160(12):1797-802. doi: 10.1001/archinte.160.12.1797

Sumithran P, Proietto J. The defence of body weight: a physiological basis for weight regain after weight loss. Clin Sci (Lond). 2013;124(4):231-41. doi: 10.1042/CS20120223

Stegen S, Derave W, Calders P, Van Laethem C, Pattyn P. Physical fitness in morbidly obese patients: effect of gastric bypass surgery and exercise training. Obes Surg. 2011;21(1):61-70. doi: 10.1007/s11695-009-0045-y

Pouwels S, Sanches EE, Cagiltay E, Severin R, Philips SA. Perioperative Exercise Therapy in Bariatric Surgery: Improving Patient Outcomes. Diabetes Metab Syndr Obes. 2020;13:1813-1823. doi: 10.2147/DMSO.S215157

van Dijk SJ, Molloy PL, Varinli H, Morrison JL, Muhlhausler BS; Members of EpiSCOPE. Epigenetics and human obesity. Int J Obes (Lond). 2015;39(1):85-97. doi: 10.1038/ijo.2014.34

da Cruz MRR, Branco-Filho AJ, Zaparolli MR, Wagner NF, de Paula Pinto JS, Campos ACL, et al. Predictors of Success in Bariatric Surgery: the Role of BMI and Pre-operative Comorbidities. Obes Surg. 2018;28(5):1335-1341. doi: 10.1007/s11695-017-3011-0