Success of bariatric surgery: Biological perspective
DOI:
https://doi.org/10.35454/rncm.v4n4.286Keywords:
Bariatric Surgery, Metabolism, Energy BalanceAbstract
Obesity is defined as an abnormal or excessive accumulation of body fat, which can reach degrees capable of affecting health. A direct correlation is known to exist between the increase of body mass index (BMI) and the prevalence of comorbidities, resulting in a negative impact on life expectancy and public health spending. Among all treatments currently available for obesity, bariatric surgery is the one with the best results in terms of excess weight loss and remission of comorbidities, and additional positive effects on adipose tissue function, insulin sensitivity, liver fat content and function, as well as overall improvement of metabolism and, consequently, increases in long-term quality of life. Biological and metabolic improvements are possible in severely obese patients after bariatric surgery.
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Badman MK, Flier JS. The gut and energy balance: visceral allies in the obesity wars. Science. 2005;307(5717):1909-14. doi: 10.1126/science.1109951
Cavin JB, Couvelard A, Lebtahi R, Ducroc R, Arapis K, Voitellier E, et al. Differences in Alimentary Glucose Absorption and Intestinal Disposal of Blood Glucose After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy. Gastroenterology. 2016;150(2):454-64.e9. doi: 10.1053/j.gastro.2015.10.009
Ziogas IA, Zapsalis K, Giannis D, Tsoulfas G. Metabolic syndrome and liver disease in the era of bariatric surgery: What you need to know! World J Hepatol. 2020;12(10):709-721. doi: 10.4254/wjh.v12.i10.709
Angrisani L, Santonicola A, Iovino P, Formisano G, Buchwald H, Scopinaro N. Bariatric Surgery Worldwide 2013. Obes Surg. 2015;25(10):1822-32. doi: 10.1007/s11695-015-1657-z
Molin Netto BD, Earthman CP, Farias G, Landi Masquio DC, Grotti Clemente AP, Peixoto P, et al. Eating patterns and food choice as determinant of weight loss and improvement of metabolic profile after RYGB. Nutrition. 2017;33:125-131. doi: 10.1016/j.nut.2016.05.007
Holst JJ, Madsbad S, Bojsen-Møller KN, Svane MS, Jørgensen NB, Dirksen C, et al. Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss. Surg Obes Relat Dis. 2018;14(5):708-714. doi: 10.1016/j.soard.2018.03.003
Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219-34. doi: 10.1111/joim.12012
Zhang C, Zhang J, Liu Z, Zhou Z. More than an Anti-diabetic Bariatric Surgery, Metabolic Surgery Alleviates Systemic and Local Inflammation in Obesity. Obes Surg. 2018;28(11):3658-3668. doi: 10.1007/s11695-018-3400-z
Kaska L, Sledzinski T, Chomiczewska A, Dettlaff-Pokora A, Swierczynski J. Improved glucose metabolism following bariatric surgery is associated with increased circulating bile acid concentrations and remodeling of the gut microbiome. World J Gastroenterol. 2016;22(39):8698-8719. doi: 10.3748/wjg.v22.i39.8698
Laferrère B, Heshka S, Wang K, Khan Y, McGinty J, Teixeira J, et al. Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes. Diabetes Care. 2007;30(7):1709-16. doi: 10.2337/dc06-1549
Price PH, Kaizer AM, Inge TH, Eckel RH. Physical activity impacts insulin sensitivity post metabolic bariatric surgery in adolescents with severe obesity. Int J Obes (Lond). 2020;44(7):1479-1486. doi: 10.1038/s41366-020-0585-8
Berthoud HR, Morrison CD, Münzberg H. The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed? Physiol Behav. 2020;222:112959. doi: 10.1016/j.physbeh.2020.112959
Leibel RL, Seeley RJ, Darsow T, Berg EG, Smith SR, Ratner R. Biologic Responses to Weight Loss and Weight Regain: Report From an American Diabetes Association Research Symposium. Diabetes. 2015;64(7):2299-309. doi: 10.2337/db15-0004
Berthoud HR, Shin AC, Zheng H. Obesity surgery and gut-brain communication. Physiol Behav. 2011;105(1):106-19. doi: 10.1016/j.physbeh.2011.01.023
Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, et al. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med. 2002;346(21):1623-30. doi: 10.1056/NEJMoa012908
Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Aminian A, Brethauer SA, et al. Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes. N Engl J Med. 2017;376(7):641-651. doi: 10.1056/NEJMoa1600869
Melby CL, Paris HL, Foright RM, Peth J. Attenuating the Biologic Drive for Weight Regain Following Weight Loss: Must What Goes Down Always Go Back Up? Nutrients. 2017;9(5):468. doi: 10.3390/nu9050468
Foright RM, Presby DM, Sherk VD, Kahn D, Checkley LA, Giles ED, et al. Is regular exercise an effective strategy for weight loss maintenance? Physiol Behav. 2018;188:86-93. doi: 10.1016/j.physbeh.2018.01.025
Andrew CA, Umashanker D, Aronne LJ, Shukla AP. Intestinal and Gastric Origins for Diabetes Resolution After Bariatric Surgery. Curr Obes Rep. 2018;7(2):139-146. doi: 10.1007/s13679-018-0302-2
Stylopoulos N, Davis P, Pettit JD, Rattner DW, Kaplan LM. Changes in serum ghrelin predict weight loss after Roux-en-Y gastric bypass in rats. Surg Endosc. 2005;19(7):942-6. doi: 10.1007/s00464-004-8825-x
Jakobsen GS, Småstuen MC, Sandbu R, Nordstrand N, Hofsø D, Lindberg M, et al. Association of Bariatric Surgery vs Medical Obesity Treatment With Long-term Medical Complications and Obesity-Related Comorbidities. JAMA. 2018;319(3):291-301. doi: 10.1001/jama.2017.21055
Mackenzie H, Markar SR, Askari A, Faiz O, Hull M, Purkayastha S, et al. Obesity surgery and risk of cancer. Br J Surg. 2018;105(12):1650-1657. doi: 10.1002/bjs.10914
Sjöström L, Narbro K, Sjöström CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741-52. doi: 10.1056/NEJMoa066254
Sjöström L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683-93. doi: 10.1056/NEJMoa035622
Karason K, Lindroos AK, Stenlöf K, Sjöström L. Relief of cardiorespiratory symptoms and increased physical activity after surgically induced weight loss: results from the Swedish Obese Subjects study. Arch Intern Med. 2000;160(12):1797-802. doi: 10.1001/archinte.160.12.1797
Sumithran P, Proietto J. The defence of body weight: a physiological basis for weight regain after weight loss. Clin Sci (Lond). 2013;124(4):231-41. doi: 10.1042/CS20120223
Stegen S, Derave W, Calders P, Van Laethem C, Pattyn P. Physical fitness in morbidly obese patients: effect of gastric bypass surgery and exercise training. Obes Surg. 2011;21(1):61-70. doi: 10.1007/s11695-009-0045-y
Pouwels S, Sanches EE, Cagiltay E, Severin R, Philips SA. Perioperative Exercise Therapy in Bariatric Surgery: Improving Patient Outcomes. Diabetes Metab Syndr Obes. 2020;13:1813-1823. doi: 10.2147/DMSO.S215157
van Dijk SJ, Molloy PL, Varinli H, Morrison JL, Muhlhausler BS; Members of EpiSCOPE. Epigenetics and human obesity. Int J Obes (Lond). 2015;39(1):85-97. doi: 10.1038/ijo.2014.34
da Cruz MRR, Branco-Filho AJ, Zaparolli MR, Wagner NF, de Paula Pinto JS, Campos ACL, et al. Predictors of Success in Bariatric Surgery: the Role of BMI and Pre-operative Comorbidities. Obes Surg. 2018;28(5):1335-1341. doi: 10.1007/s11695-017-3011-0
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Copyright (c) 2021 Edna J Nava-González, Brenda K. Delgadillo Arteaga
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