Incertidumbre clínica durante la prescripción de proteína al paciente en estado crítico de Latinoamérica

Luis Alfonso Ortiz-Reyes; Daren Heyland

doi:10.35454/rncm.v2n1.058

Authors

Luis Alfonso Ortiz-Reyes https://orcid.org/0000-0003-2626-1279
Daren Heyland https://orcid.org/0000-0002-6440-4616

DOI:

https://doi.org/10.35454/rncm.v2n1.058

Keywords:

EFFORT, Critical care, Protein dose, Nutritional support, Clinical trials bases on records

Abstract

The guidelines recommendation for protein dose in critically ill patients is 1.2 - 2.0 g/kg/d. Despite this recommendation, the actual amount delivered ranks between 0.5 and 3.8 g/kg/d therefore there is significant controversy in the amount of protein prescribed and delivered worldwide. This review approach
the clinical equipoise, or a state of genuine uncertainty about two (dosing) strategies for protein dose. In addition, highlight the limited contribution of Latin American (LATAM) patients in published Randomized Clinical Trials (ECAs) questioning the generalizability of their results. This manuscript outline evidence
for and against high protein dose and introduce the EFFORT trial which aims to answer the important question of what protein dose is the best for what type of patient?

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